{"id":280,"date":"2016-12-22T10:21:37","date_gmt":"2016-12-22T10:21:37","guid":{"rendered":"http:\/\/www.iuibs.ulpgc.es\/?p=280"},"modified":"2016-12-22T10:21:37","modified_gmt":"2016-12-22T10:21:37","slug":"the-rebound-effect-and-diabetes","status":"publish","type":"post","link":"https:\/\/www.iuibs.ulpgc.es\/web-grupos\/blog\/2016\/12\/22\/the-rebound-effect-and-diabetes\/","title":{"rendered":"The \u00abrebound effect\u00bb and diabetes"},"content":{"rendered":"<p><span id=\"result_box\" class=\"\" lang=\"en\"><span title=\"Especialistas del Grupo de Investigaci\u00f3n Biom\u00e9dica en Red-Fisiopatolog\u00eda de la Obesidad y la Nutrici\u00f3n indican que existe una predisposici\u00f3n a desarrollar diabetes mellitus tipo 2 en aquellos pacientes que han vuelto a ganar peso tras haberlo perdido en una dieta.\n\">Specialists from the Biomedical Research Group in Red-Pathophysiology of Obesity and Nutrition indicate that there is a predisposition to develop type 2 diabetes mellitus in those patients who have regained weight after losing it in a diet.<br \/>\n<\/span><span title=\"Los investigadores estudiaron a un grupo de 136 pacientes obesos que siguieron una dieta hipocal\u00f3rica de ocho semanas para bajar de peso y que, al finalizarla, trataron de mantenerse en el peso alcanzado.\n\n\">The researchers studied a group of 136 obese patients who followed an eight-calorie, low-calorie, weight-loss diet and, at the end of the week, tried to stay at their full weight.<\/p>\n<p><\/span><span title=\"Entre cuatro y seis meses despu\u00e9s del tratamiento, fueron reevaluados para comprobar si hab\u00edan alcanzado su objetivo y hab\u00edan logrado evitar el llamado \u201cefecto rebote\u201d, que suele producirse en algunos pacientes tras este tipo de restricciones alimentarias.\n\n\">Between four and six months after treatment, they were re-evaluated to see if they had achieved their goal and had managed to avoid the so-called \u00abrebound effect\u00bb, which usually occurs in some patients after this type of dietary restrictions.<\/p>\n<p><\/span><span title=\"\u201cEn las evaluaciones que se les realizaron se atendi\u00f3, de forma especial, a los niveles de irisina, leptina y adiponectina, para determinar la diferencia entre las cantidades iniciales, al final de la dieta y despu\u00e9s del periodo de seguimiento.\">\u00abIn the evaluations that were performed, the levels of irisine, leptin and adiponectin were used in order to determine the difference between the initial amounts, at the end of the diet and after the follow-up period. <\/span><span title=\"Los resultados no dejaron lugar a dudas: de los 136 pacientes analizados, el 50% recuper\u00f3 el peso perdido y, despu\u00e9s de comprobar sus anal\u00edticas y observar altos niveles de irisina en sangre, fueron clasificados como resistentes a la insulina\u201d, se\u00f1ala Ana Bel\u00e9n Crujeiras\">The results left no doubt: of the 136 patients analyzed, 50% recovered their lost weight and, after checking their analytics and observing high levels of irisin in blood, were classified as resistant to insulin, \u00absays Ana Bel\u00e9n Crujeiras <\/span><span title=\", autora principal del estudio.\">, Lead author of the study.<\/span><\/span><\/p>\n<p><span id=\"result_box\" class=\"\" lang=\"en\"><span title=\"Hormonas\n\n\"><strong>Hormones<\/strong><\/p>\n<p><\/span><span title=\"Crujeiras explica que la leptina y la adiponectina son liberadas por el tejido graso de nuestro organismo.\">Crujeiras explains that leptin and adiponectin are released by the fatty tissue of our body. <\/span><span title=\"\u201cLa leptina tiene como funci\u00f3n disminuir el apetito y, adem\u00e1s, est\u00e1 relacionada con la regulaci\u00f3n del metabolismo.\">\u00abLeptin has the function of decreasing appetite and, in addition, is related to the regulation of metabolism. <\/span><span title=\"Por su parte, la adiponectina tiene que ver con el metabolismo de la glucosa y es una hormona protectora\u201d, indica la experta.\n\n\">Adiponectin has to do with glucose metabolism and is a protective hormone, \u00absays the expert.<\/p>\n<p><\/span><span title=\"\u201cLos sujetos obesos tienen niveles muy altos de leptina, a pesar de que es una hormona que disminuye el apetito.\">\u00abObese subjects have very high levels of leptin, even though it is a hormone that lowers the appetite. <\/span><span title=\"Mientras, la adiponectina est\u00e1 muy disminuida y se asocia con los fallos que tienen las personas obesas en el metabolismo de la glucosa\u201d, afirma Crujeiras.\n\">Meanwhile, adiponectin is greatly diminished and is associated with the failures of obese people in glucose metabolism, \u00absays Crujeiras.<br \/>\n<\/span><span title=\"Seg\u00fan indica la m\u00e9dico especialista, la irisina fue descubierta hace solo un a\u00f1o y gener\u00f3 grandes expectativas como protectora ante la obesidad.\">According to the specialist doctor, the irisine was discovered only a year ago and generated high expectations as a protector against obesity. <\/span><span title=\"En un principio, se descubri\u00f3 que era secretada por el m\u00fasculo despu\u00e9s de hacer ejercicio y se propuso como protectora para combatir la obesidad y mejorar el metabolismo de la glucosa.\n\n\">At first, it was discovered that it was secreted by the muscle after exercise and was proposed as a protector to combat obesity and improve glucose metabolism.<\/p>\n<p><\/span><span title=\"\u201cNosotros observamos que tambi\u00e9n la secretaba el tejido adiposo y encontramos que los pacientes obesos ten\u00edan los niveles de irisina aumentados.\">\u00abWe observed that it was also secreted by adipose tissue and found that obese patients had increased irisine levels. <\/span><span title=\"Adem\u00e1s, hemos hallado una asociaci\u00f3n entre la irisina, la resistencia a la insulina y volver a ganar peso despu\u00e9s de una dieta\u201d, apunta.\">In addition, we have found an association between irisine, insulin resistance and regain weight after a diet, \u00abhe says.<\/span><\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Specialists from the Biomedical Research Group in Red-Pathophysiology of Obesity and Nutrition indicate that there is a predisposition to develop type 2 diabetes mellitus in those patients who have regained weight after losing it in a diet. The researchers studied a group of 136 obese patients who followed an eight-calorie, low-calorie, weight-loss diet and, at [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":232,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[17],"tags":[],"class_list":["post-280","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-sin-categoria-en"],"blocksy_meta":[],"_links":{"self":[{"href":"https:\/\/www.iuibs.ulpgc.es\/web-grupos\/wp-json\/wp\/v2\/posts\/280","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.iuibs.ulpgc.es\/web-grupos\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.iuibs.ulpgc.es\/web-grupos\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.iuibs.ulpgc.es\/web-grupos\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.iuibs.ulpgc.es\/web-grupos\/wp-json\/wp\/v2\/comments?post=280"}],"version-history":[{"count":1,"href":"https:\/\/www.iuibs.ulpgc.es\/web-grupos\/wp-json\/wp\/v2\/posts\/280\/revisions"}],"predecessor-version":[{"id":281,"href":"https:\/\/www.iuibs.ulpgc.es\/web-grupos\/wp-json\/wp\/v2\/posts\/280\/revisions\/281"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.iuibs.ulpgc.es\/web-grupos\/wp-json\/wp\/v2\/media\/232"}],"wp:attachment":[{"href":"https:\/\/www.iuibs.ulpgc.es\/web-grupos\/wp-json\/wp\/v2\/media?parent=280"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.iuibs.ulpgc.es\/web-grupos\/wp-json\/wp\/v2\/categories?post=280"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.iuibs.ulpgc.es\/web-grupos\/wp-json\/wp\/v2\/tags?post=280"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}